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approaching the shared biology of obesity and depression the stress axis as the locus of gene–environment interactions

Tài liệu Báo cáo khoa học: Mechanisms of obesity and related pathologies: Androgen deficiency and endothelial dysfunction may be the link between obesity and erectile dysfunction pptx

Tài liệu Báo cáo khoa học: Mechanisms of obesity and related pathologies: Androgen deficiency and endothelial dysfunction may be the link between obesity and erectile dysfunction pptx

Báo cáo khoa học

... abdominal (visceral) obesity and thatthis type of obesity contributes to insulin resistance(IR) and the increased release of cytokines, as well as the impairment, clearance and storage of triglyceridesin ... causes vasodilation, and increases blood flow to the corpus cavernosum. The increased blood flow stimulates the endothelium lining the lacunar spaces of the corpus cavernosum to releaseendothelial ... system, as well as the vascularbed of the penis, and depends on a functional veno-occlusive mechanism [3]. The latter is maintained by the hormonal milieu. Thus, androgen deficiency and endothelial...
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Báo cáo khoa học: Mechanisms of obesity and related pathologies: Role of apolipoprotein E in the development of obesity potx

Báo cáo khoa học: Mechanisms of obesity and related pathologies: Role of apolipoprotein E in the development of obesity potx

Báo cáo khoa học

... cells in the form of triglycerides, leads to the development of obesity. Despite the pivotal role of obesity and dyslipide-mia in the development of the metabolic syndrome and heart disease, the functional ... the pivotal role of obesity and dyslipidemia in the development of the metabolic syndrome and heartdisease, the functional interactions between adipose tis-sue and the lipid and lipoprotein transport ... protein of the lipid and lipoprotein transport system mainlyinvolved in the metabolism of dietary lipids and the removal of atherogenic lipoproteins, such as chylomi-cron remnants and very...
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Báo cáo y học:

Báo cáo y học: "Thioglycosides as inhibitors of hSGLT1 and hSGLT2: Potential therapeutic agents for the control of hyperglycemia in diabetes"

Y học thưởng thức

... hydrolysis-resistant, synthetic S-analogs of natural O-glucosides involved in the bio-synthesis of chrysomelidial and salicin. These sub-stances are synthesized and secreted as part of a de-fense mechanism ... larvae of beetles (Chry-somelidae). Their synthesis has been previously de-scribed [31-33]. For the purpose of the present study the thioglycosides used were selected and grouped based on their ... and luminescence for ATP detection was assessed using a MicroBeta Trilux (PerkinElmer). A standard curve was used to determine the amount of ATP in mg of protein measured from the number of...
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The meaning of tingo and other extraordinary words from around the world

The meaning of tingo and other extraordinary words from around the world

Anh ngữ phổ thông

... family. The Sakalavas of Madagascar do not tell their own name or that of their village to strangers to prevent any mischievous use. The Todas of Southern India dislike uttering their own name and, ... both of the right kind, as in kontal-kontil, the swinging of long earrings or the swishing of a dress as one walks’, and the wrong, as in jerangkang, ‘to fall over with your legs in the air’. ... The scanning, uploading and distribution of this book via the Internet or via any other means without the permission of the publisher is illegal and punishable by law. Please purchase only...
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Tài liệu Báo cáo khoa học: Angiopoietin-like proteins: emerging targets for treatment of obesity and related metabolic diseases pptx

Tài liệu Báo cáo khoa học: Angiopoietin-like proteins: emerging targets for treatment of obesity and related metabolic diseases pptx

Báo cáo khoa học

... countries. These conditions are asso-ciated with increased risk of cardiovascular disease, the leading cause of death. Therefore, it is important to understand the molecular basis underly-ing obesity ... increase in obesity due to lifestylechanges, such as inactivity and overnutrition, is anincreasing medical and social problem in developed and developing countries [1]. Obesity increases the ... adipose tissue in obesity and related insulin resistance [15]. Here, we focus on the roles of ANGPTL2 and ANGPTL6 ⁄ AGF in obes-ity and related metabolic diseases, and discuss whetherthese ANGPTLs...
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Tài liệu A Comparison of Conventional and Organic Milk Production Systems in the U.S. potx

Tài liệu A Comparison of Conventional and Organic Milk Production Systems in the U.S. potx

Cao đẳng - Đại học

... cows), and their mean size was not statistically different from the mean size of conventional operations (431 cows). The mean size of organic dairies in the Northeast was only half the size of ... adopting the organic approach because of access to high quality pastures and the ability to manage pasture as a dairy feed source. These areas also have a long history of small dairy operations and ... prohibit the use of antibiotics and hormones in the cow herd and the use of synthetic chemicals in the production of cattle feed. Organic milk production systems also attempt to accommodate the...
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Báo cáo khoa học: Assessment of porcine and human 16-ene-synthase, a third activity of P450c17, in the formation of an androstenol precursor doc

Báo cáo khoa học: Assessment of porcine and human 16-ene-synthase, a third activity of P450c17, in the formation of an androstenol precursor doc

Báo cáo khoa học

... Cytochrome b5has a much stronger effect on the 16-ene-synthase activity than on the 17a-hydroxylase/17,20-lyase activities. On the other hand, P450reductase hasa drastic effect on the latter, but ... substrate. As observed in Fig. 3, the biosynthesis of androstadienol in humans (A) and pigs (B)does not require prior formation of 17a-OH-preg and DHEA. The lack of androstadienol synthesis in the ... amounts of DNA fragments encoding cyt b5 and monitored the formation of androstadienol and DHEA. As shown inFig. 5 the stimulation of DHEA and androstadienolproduction from preg increases with...
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Báo cáo khoa học: The oxidative effect of bacterial lipopolysaccharide on native and cross-linked human hemoglobin as a function of the structure of the lipopolysaccharide A comparison of the effects of smooth and rough lipopolysaccharide ppt

Báo cáo khoa học: The oxidative effect of bacterial lipopolysaccharide on native and cross-linked human hemoglobin as a function of the structure of the lipopolysaccharide A comparison of the effects of smooth and rough lipopolysaccharide ppt

Báo cáo khoa học

... mediated by the smooth LPSwas less affected by the presence of EDTA. The roughS. minnesota LPS increased the initial fast phase of the reaction, but decreased the rate of the slow phase of oxidation ... comparison of the effects of roughandsmoothLPSsofE. coli, both in the presence and absence of EDTA (Fig. 1). The rate of oxidation wasincreased in the presence of the LPSs of both the smooth and rough ... shown). The decrease inconcentration of oxyHb with time was utilized as a measure of the rate of oxidation of oxyHb.RESULTS The effect of pH on the auto-oxidation of cross-linked Hbwas studied. The...
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Preferences of the Central Reserve Bank of Peru and optimal monetary policy rules in the inflation targeting regime ppt

Preferences of the Central Reserve Bank of Peru and optimal monetary policy rules in the inflation targeting regime ppt

Ngân hàng - Tín dụng

... the macroeconomic model (1)-(4) was estimated. As the nominal exchange rate is assumed to follow a random walk, the estimation was based only on the demand and aggregate supply, and terms of ... corresponding to an increase in the price of metals such as copper, gold, zinc, among others. This increase was based on the heated economic growth of China, the major importer of Peru’s raw materials.25 ... 2006:02 and 0, otherwise) and ,2ttd (=1 2007:02 and 0, otherwise) were added for the terms of trade equation in order to capture the large growth of the terms of trade due to an increase in...
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Báo cáo Y học: Functional integration of mitochondrial and hydrogenosomal ADP/ATP carriers in the Escherichia coli membrane reveals different biochemical characteristics for plants, mammals and anaerobic chytrids pdf

Báo cáo Y học: Functional integration of mitochondrial and hydrogenosomal ADP/ATP carriers in the Escherichia coli membrane reveals different biochemical characteristics for plants, mammals and anaerobic chytrids pdf

Báo cáo khoa học

... producing the higher expressedplant and mammalian AAC proteins (Fig. 1). The unde-fined TB medium and the addition of pyruvate and malatestimulated the bacterial metabolism and led to the genera-tion ... Kaiserslautern, Germany;2Department of Evolutionary Microbiology, Faculty of Science,Catholic University of Nijmegen, the Netherlands The expression of mitochondrial and hydrogenosomalADP/ATP carriers ... mitochondrial-type AACsin order to identify differences in the function of the variousisoforms and to understand the repeated evolution of AACisoforms in a variety of organisms.We have shown earlier that it...
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Báo cáo

Báo cáo " The dependence of the parametric transformation coefficient of acoustic and optical phonons in doped superlattices on concentration of impurities" pot

Báo cáo khoa học

... concentration of impurities, m and e are the effective mass and the charge of the electron, respectively and ne are the energy levels of an individual well. In order to establish a set of quantum ... same kinds of excitations such as phonon-phonon, plasmon-plasmon, or of different kinds of excitations, such as plasmon-phonon will arise; i.e., the energy exchange process between these excitations ... (10) where, the quantity δ is infinitesimal and appears due to the assumption of an adiabatic interaction of the electromagnetic wave (EMW). In Eq.(8), the first term on the right-hand side...
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Báo cáo khóa học: Structural and functional comparison of 15S- and 15R-specific cyclooxygenases from the coral Plexaura homomalla potx

Báo cáo khóa học: Structural and functional comparison of 15S- and 15R-specific cyclooxygenases from the coral Plexaura homomalla potx

Báo cáo khoa học

... similar conversion of the radio-labelled substrate. The Val349Ile mutant of the 15S-COXformed 65% PGF2a and 35% of the 15R-epimer of PGF2a.In the case of the 15R-COX, the Ile349Val mutation ... that the other 16 residues lie outside of the active site and mostly on the surface of the catalyticglobular domain of the COX protein.Protein expression and product analysis The cDNA was cloned ... 349 in the specificities of the two P. homomalla variants, a Val349Ilemutant of the 15S-COX and an Ile349Val mutant of the 15R-COX were prepared and e xpressed in the b aculovirussystem. The mutants...
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Báo cáo khoa học: The binding of foot-and-mouth disease virus leader proteinase to eIF4GI involves conserved ionic interactions ppt

Báo cáo khoa học: The binding of foot-and-mouth disease virus leader proteinase to eIF4GI involves conserved ionic interactions ppt

Báo cáo khoa học

... and therefore is independ-ent of the interaction between eIF4E and eIF4G[10,11]. The picornaviral proteinases such as the leaderproteinase (Lpro) of foot -and- mouth-disease virus(FMDV) and ... efficiency of the pull-down is probablylimited by the presence of the GST part of the fusionprotein, the small size of the radiolabelled fragment and the probability that a certain fraction of bothbinding ... furthermore, the extent of binding correlated with the effect of these mutationson eIF4GI. The mutants GST–LbproC51AD184A and Fig. 4. Substitution of residues D184 and E186 in the CTE of FMDV...
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STOCK ASSESSMENT AND FISHERY EVALUATION REPORT FOR THE GROUNDFISH FISHERIES OF THE GULF OF ALASKA AND BERING SEA/ALEUTIAN ISLANDS AREA: ECONOMIC STATUS OF THE GROUNDFISH FISHERIES OFF ALASKA, 2008 potx

STOCK ASSESSMENT AND FISHERY EVALUATION REPORT FOR THE GROUNDFISH FISHERIES OF THE GULF OF ALASKA AND BERING SEA/ALEUTIAN ISLANDS AREA: ECONOMIC STATUS OF THE GROUNDFISH FISHERIES OFF ALASKA, 2008 potx

Cao đẳng - Đại học

... SAFESTOCK ASSESSMENT AND FISHERY EVALUATION REPORT FOR THE GROUNDFISH FISHERIES OF THE GULF OF ALASKA AND BERING SEA/ALEUTIAN ISLANDS AREA: ECONOMIC STATUS OF THE GROUNDFISH FISHERIES OFF ALASKA, ... $368 million or 21% of the total Alaska ex-vessel value. The value of the shellfish fishery amounted to $252 million or 15% of the total for Alaska and exceeded the value of Pacific halibut ... indicated that they were not residents of Alaska. Vessels with owners who indicated that they were residents of Alaska accounted for 13% of the total. The vessels owned by residents of Alaska accounted...
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Báo cáo khoa học: Mechanisms of obesity and related pathologies: Transcriptional control of adipose tissue development pdf

Báo cáo khoa học: Mechanisms of obesity and related pathologies: Transcriptional control of adipose tissue development pdf

Báo cáo khoa học

... adipose tissuemass [1]. Consequently, obesity has a significant coston the well being of society because the incidence of these diseases is expected to double by the year 2030 and the associated ... investigators with the new challenge of howto increase its mass and ⁄ or activity as a part of ananti -obesity therapy. Additional knowledge of the molecular mechanisms controlling the formation of alladipose ... preadipocytes, vascular cells such as endo-thelial and pericytes, as well as immune cells. The SVFis considered to be a source of adipocyte precursorsbecause of the presence of cells within...
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